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KMID : 1101420150470010039
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Korean Journal of Clinical Laboratory Science
2015 Volume.47 No. 1 p.39 ~ p.45
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Genotype Analysis of Human Papilloma Virus Infection in Accordance with Cytological Diagnoses
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Park Mi-Suk
Cho Hyun-Wook
Kim Jin-Gak
Bae Nan-Young
Oh Dong-Sun
Park Ho-Hyun
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Abstract
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We investigated whether multiple infections can be used as predictors of progression to carcinogenesis in accordance with the cytological diagnosis in women receiving abnormal cytologic diagnosis as analysis genotype and compared to single infection. HPV prevalence is highest in the age of under 30 years old woman, HPV prevalence is started to lower after 30 years old and started to increase over 60 years old as like a U-shape. The specific HPV genotypes is an important factor because increased single infection and reduced multiple infections and appeared single infection with AC in progressing carcinogenesis. HPV 16 revealed the statistical significance at the single infection in squamous cell lesions, and HPV 18 revealed the statistical significance at the single infection in adenocarcinoma with showed HPV 16, 58, 18, 52-type distribution.
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KEYWORD
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Cytological, Human papilloma virus, Genotype, Multiple infection
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